In Staphylococcus saprophyticus the surface-associated protein ( Ssp) has been previously characterized as a cell wall-associated true lipase. Staphylococcal lipases have been proposed as pathogenicity factors. Staphylococcus saprophyticus surface-associated protein ( Ssp) is associated with lifespan reduction in Caenorhabditis elegans About a dozen species are frequently carried on humans, including Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus capitis, Staphylococcus hominis, Staphylococcus cohnii, Staphylococcus lugdunensis, Staphylococcus schleiferi, Staphylococcus saprophyticus, Staphylococcus simulans, Staphylococcus warneri and Staphylococcus xylosus. ![]() There are over 30 species of staphylococci identified, and they are typically found on the skin and mucous membranes of mammals. By 16S ribosomal sequencing, they are most closely related to the Gram-positive, low G+C content Bacillus-Lactobacillus- Staphylococcus genera (Woese, 1987). The staphylococci are Gram-positive cocci that divide to form clusters that look like grapes. elegans and one could speculate that the lipase activity itself is responsible for this virulence. These results indicate that the Ssp is associated with pathogenicity in C. In order to attribute virulence to the lipase activity itself and distinguish this phenomenon from the presence of the Ssp-protein, the conserved active site of the lipase was modified by site-directed ligase-independent mutagenesis and lipase activity-deficient mutants were constructed. saprophyticus Δ ssp::ermB mutants lifespan reduction in C. saprophyticus induced a lifespan reduction in Caenorhabditis elegans similar to that of S. saprophyticus Δ ssp::ermB mutant has been described as less virulent in an in vivo model of urinary tract infection compared with its wild-type. Szabados, Florian Mohner, Amelie Kleine, Britta Gatermann, Sören G ![]() Staphylococcus saprophyticus surface-associated protein ( Ssp) is associated with lifespan reduction in Caenorhabditis elegans. The SW120 draft genome is 2,805,064 bp and contains 2,667 coding sequences, including 58 tRNAs and nine complete rRNA coding regions. The isolate is resistant to methicillin and fusidic acid. urealyticus strain SW120 was isolated from the ear swab of a healthy dog. urealyticus Isolated from a Healthy DogĪBSTRACT  Staphylococcus cohnii subsp. Draft Genome Sequence of Staphylococcus cohnii subsp.
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